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The bioelectronic medicine start-up studio

The bioelectronic medicine start-up studioThe bioelectronic medicine start-up studioThe bioelectronic medicine start-up studio

We are on a mission to change how medical devices interact with nerves to treat chronic disorders

arun@artha-health.com

The bioelectronic medicine start-up studio

The bioelectronic medicine start-up studioThe bioelectronic medicine start-up studioThe bioelectronic medicine start-up studio

We are on a mission to change how medical devices interact with nerves to treat chronic disorders

arun@artha-health.com

Who are we?

Artha Health aims to create new therapies for chronic disorders. We believe that the biggest opportunity to develop far-reaching therapies lies in delineating novel nerve targets and mechanisms of action that these nerves impact. This helps us define, design, and develop novel bioelectronic medicines. 

Why neuromodulation?

What is a bioelectronic medicine?

Bioelectronic medicine refers to medical devices that interact with nerves or nerve structures in the body to modulate the electrical signalling in the nerves (called action potentials) to treat chronic disorders. Our body has an intricate wiring of nerves that are dynamically regulated every second. While offering therapeutic benefit, current devices like deep brain stimulation, spinal cord stimulation and cranial nerve stimulation devices are the only targets exploited for therapeutic benefit. They suffer from lack specificity and are often the last resort therapy. 


At Artha Health, we aim to change the current state by discovery of novel nerve targets and mechanisms to define how neuromodulation should be performed across a range of diseases. 

Our Vision

 

At Artha Health, we believe that technological advancements should go hand-in hand with improving our understanding of how autonomic nerves (outside the brain and spinal cord) that are closer to the end organ, control disease. These nerve targets are ideal for intervention as they provide greater specificity and less adverse effects than traditional pharmaceutical or neuromodulatory device approaches. 

We aim to define the best "nodal" intervention points along their hierarchy to treat disease. The targeting technologies (spatial and temporal) must be bespoke for the disease need, patient population and influence adherence to therapy.

Deep Roots

Artha Health is founded by a leading innovator in the field, Arun Sridhar. He was the architect of the portfolio for GSK bioelectronics R&D; that eventually led to the formation of Galvani Bioelectronics and subsequent $700 million investment from GSK and Verily. 

Arun founded Artha Health to develop future therapies targeting novel nerve targets, most of which are largely underserved. The opportunity to invent and innovate is vast. 

 

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Artha (Ar-Thaa) is a sanskrit word & translates to "sense, goal or purpose"

Everyone in neuromodulation today is running around like a "hammer looking for a nail". Neuromodulation innovation today, evolved from pacemaker technology and the market priority is to grab a portion of what existing market leaders have by introducing incremental technological improvements rather than identify new targets. 





Why the current innovation model doesn't work

If one is to move beyond the traditional neurological disease paradigms, the richness and opportunity offered by peripheral autonomic nerves must be explored. In layman's terms, the technology (hammer or screwdriver) should be determined by the type of screw or nail. 

How do we seek to change the status quo?

We are on a mission to find novel neural targets, translate the mechanisms, understanding how the nested loops within nervous system responds to a "dose" and thereby provide "Artha" to neuromodulation.


 This will ensure electrical impluses become the mainstay of treatment to sit alongside existing treatment paradigms and not as the last resort. 

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